Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the therapy of many myeloma. Its synthesis or review is vital for making certain the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound inside the synthesis of imatinib, a drug that targets specific forms of most cancers, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their review is essential for optimizing the creation course of action and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast most cancers, and these intermediates are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the remedy of colorectal most cancers and little cell lung CAS NO.827026-45-9 cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is linked to the synthesis of adamantane derivatives, that have numerous programs, like antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type 2 diabetes that inhibits the enzyme CAS NO. 875573-63-0 DPP-4 to control blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of various gluconic acid derivatives, that are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication used to deal with form 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).